Board Thread:Questions and Answers/@comment-39692887-20190604013739/@comment-39563968-20190615012928

(Spoiler Warning - not blatant, for any who are likely to have read this OP, but possible)

Most sources / nodes for resources do not appear to respawn.

Not sure about major drillable deposits or Reefback barnacles.

Even mushrooms / other plants may not respawn in the wild, though of course you CAN grow the critical types in beds.

For a number of common resources, including most of those commonly used in base building, this may not be a problem, if you are willing to be an exhaustively thorough miner / scavenger. For example: There are tens of thousands of units of titanium in/on the Crater.

Quartz could conceivably be a problem, use it sparingly. But the deeper you build, the less you use glass, even enameled glass, so maybe not.

Most of the really unusual stuff is used for fairly unique projects.

Hmm. At a guess, the real resource pinch might be silver. Again, use it as sparingly as you can.

Run your power off as much as possible off truly renewable stuff like massive solar farms and thermal generator ring farms, with extensive power transmission.

You could, of course, play in Creative Mode after you have finished the adventure. Then resources really are unlimited.